The high quality air indoor automatic regulation system is designed in the paper. The system is used to detect air temperature, humidity, PM2.5 concentration, formaldehyde content, smoke concentration and other physical quantities. The system is composed of the main controller and different types of sensors. The controller can not only control the working state of each sensor, but also set the measured physical threshold. When the real-time measurement value of smoke, formaldehyde, PM2.5 concentration and temperature exceeds the set threshold, the buzzer will alarm and automatically start the air purification device. The system is used to measure the actual indoor environmental parameters. The experimental results show that the indoor air conditioning system can realize the environmental monitoring and purification of the indoor living environment of families, and provide guarantee for people to live in a high-quality air environment, which is the development direction of smart home design in the future.